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1、Lecturer:Guo Xiang,Classification and Diagnosis of astrocytoma(星形细胞瘤),Morbidity of Astrocytoma,5-10,100000,Morbidity,Type of Astrocytoma,WHO classification,级 毛细胞型星形细胞瘤、室管膜下巨细胞星形细胞瘤,级弥漫型星形细胞瘤,级间变型星形细胞瘤,级胶质母细胞瘤,Pilocytic astrocytoma AND Subependymal giant cell astrocytomas,Diffuse astrocytoma,Anaplast
2、ic astrocytoma,Glioblastoma,Subependymal giant cell astrocytomas-Grade,epiloia(结节性硬化)8Y18Y(male-to-female ratio=3:1)subependymal nodules contrast-enhance hydrocephalus脑积水 favorable clinical outcome,红黄色丘疹,M 16y,Pilocytic astrocytoma-Grade,ChildrenCerebellum hemispheres or vermisSolid and cystic partN
3、ormal tissuesolid nodulecystic massCSF in density on NCCTMRI:a high-signal-intensity cyst surrounding a iso-intensity mural nodule on T2Contrast enhancement with both CT and MRI,vermis,F 62Y,T1,T2,T1-enhance,Pathology,弥漫型星形细胞瘤属于交界性肿瘤,容易复发,且恶性度有不断增加的趋势,最终发展为胶质母细胞瘤。,Grade-Diffuse astrocytoma,Grade-Ana
4、plastic astrocytoma,Grade-Glioblastoma,Diffuse astrocytoma-Grade,borderline tumor surgery,malignancy will be higher,recur,Characteristic,Imaging Characteristic,Brainstem or supratentorial white matterpoorly defined borderLow-density on CT slightlyCSFNo significant enhancement,No or slightly enhancem
5、ent,Cystic change,T1WI hypointensity signal T2WI hyperintensity signal,F 54Y,Surgical field and Specimen,The tumor showed diffusely infiltrated growing.NO hemorrhage and necrosis.,Anaplastic astrocytoma-Grade,the tumor enhanced distinctly,T1-enhance,FLAIR,T1,T2,T1,Glioblastoma-Grade-,Adulthood Mixed density or signal lesionHemorrhage and necrosis Contrast-enhance,Because the treatment of astrocytoma is mainly based on pathological type,so it will be very helpful to make an accurate diagnosis to the level of cells.,Thank You!,Thank You for Your Attention,