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1、人 体 之 旅-从 形 态 到 分 子,四川大学基础医学与法医学院人体解剖学教研室周鸿鹰,Introduction to anatomy,What is Human AnatomyHow to study Human AnatomyAdvancement of Anatomy,What is anatomy,Anatomy is an old basic medical scienceThe study of anatomy originated in Egypt.Hippocrates-“Father of Medicine”Aristotle(384-322B.C),was the fou
2、nder of comparative anatomy.He is the first person to use the“anatomy”.,Hippocrates-希波克拉底（公元前460377）古希腊名医、解剖学鼻祖。,Galen-盖伦（130200）古希腊名医、解剖学家，著医经，对血液流动、神经分支和脑、心等器官有具体描述。,Vesalius-(15141564)现代解剖学的奠基人，1543年出版了人体构造这一划时代的解剖学巨著,Harvey-(15781657)解剖生理学家，发现了血液循环的原理，确定血液是在一个封闭的管道内循环。著有血液循环论、动物的发生两书。开创了动物实验研究的道
3、路。,我国人体解剖学,公元前300200黄帝内经已有对人体解剖的记载。两宋时代五脏六腑、存真图描述了解剖学知识。王清任（17681831）编著的医林改错更为详细的描述了解剖学知识。19492003年我国解剖学工作者队伍迅速成长，编写了多套具有我国特色的解剖学教材和解剖学图谱，对我国解剖学事业的发展做出了巨大的贡献。,Anatomy is basic medical sciencesAnatomy is the study of structure and functionAnatomy has formed foundation for students in medical career,W
4、hat is anatomy,What is Human Anatomy,Studying of the structures,organs,of the human body,including:shape,size,position blood supply,innervations relationship:the structures and organs their functions,Approaches to studying anatomy:Regional anatomy,It is the study of human body by regions.The regions
5、 usually designated are:Head NeckThorax(chest)AbdomenPelvis and perineum,back Lower limbUpper limb,The regions of the human body:,Approaches to studying anatomy:Systemic anatomy,Acculomotor systemDigestive systemRespiratory systemUrinary systemReproductive systemCirculatory systemEndocrine systemNer
6、vous system,Acculomotor system,Digestive system,Respiratory system,Urinary&Reproductive system,Circulatory system,Endocrine system,The human nervous system,The brain occupied the cranial cavityThe spinal cord located in spinal canal,The cranial nerves attached to the brainThe spinal nerves attached
7、to spinal cord,Clinical anatomy,emphasizes aspects of structure and function of the body that are important in the practice of medicine,dentistry,and the allied health sciences.It incorporates the regional and systemic approaches and stresses clinical applications.In addition,surgical and imaging te
8、chniques(e.g.,radiography)are used to demonstrate living anatomy.Case studies are integral part of clinical anatomy.,Approaches to studying anatomy:Surface anatomy,It is impossible to examine a patient without knowledge of surface anatomy,Approaches to studying anatomy:Radiological anatomy,Radiologi
9、cal anatomy is the study of structure and function of the body using radiographic techniques.,Approaches to studying anatomy:Developmental anatomy,Developmental anatomy is the study of human growth and development.,How to study Human Anatomy,dissectobservepalpatesummary memory some factors and conce
10、ptstry to describe,How to Do It Yourselves,Before class,to know which structures and organs you will meet,and the Procedures of dissectionDuring class,to dissect,expose and palpate After class,to summarize,to describe,How to describe the structures,keep the anatomical position in your mindmaster the
11、 descriptive terms terms of relationship terms of comparisonavoid misunderstanding,Introduction of Dept.of Anatomy,四川大学人体解剖学教研室,SCU,Introduction of our department,师 资 结 构,教职工22人，其中教授2人、副教授3人、讲师9人、实验技术人员8人,课程建设,课程体系的完善 网站建设 教材引进和使用 参编、主编教材 教学获奖情况,主编、参编教材,教学获奖,科研工作框架分子解剖,四川大学人体解剖学教研室,SCU,工作框架 I,胚胎发生、发
12、育规律,器官、系统发育的时序和调控,技术手段,传统形态学手段,新分子生物学方法的应用,研究对象,模型动物,人群资料的收集,工作框架 II,手术应用精细解剖：特定器官局解、器官内神经、血管分布,微创手术入路研究,临床应用解剖,工作框架 III,糖尿病视网膜病变分子机制探讨：获取DR基因组与蛋白组变化资料；分析验证DR过程中，神经视网膜相关分子的变化,癌功能基因组学、蛋白组学研究：乳腺癌基因差异表达谱和蛋白组资料的获取、筛选；直、结肠癌候选基因；基因组差异与蛋白组差异的联系和比较,技术核心：基因组、蛋白组技术,工作程序与特色,以基因组、蛋白组整体水平入手 以重大疾病和生命最基本进程为研究对象 充分利用本领域新技术、新成果 成果转化,靶分子的功能研究和应用性探索,在“组”的整体水平筛选,“组”,建立研究对象的功能基因组、蛋白组,部分研究成果,基因组资料,蛋白组资料,关于胚胎发育,见附图,Gene expression profile of DR,2D images of DR model rats,a,d,c,b,Development of pancreas of human being,Thank You!,SCU,
