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1、临床医学文献检索、阅读、评价与应用,崔学军2011年9月15日,检索途径,题录型数据库中国生物医学文献数据库（CBM）Medline全文型数据库中文科技期刊数据库（VIP）万方数据知识平台中国知网（CNKI）,Medline检索,保存和跟踪检索结果,获取全文的途径,其他途径,中国科学院上海生命科学研究院复旦大学上海医学院上海图书馆交通大学,Google 题目英文关键词 filetype:PDF联系作者论坛代理,重要工具,华东地区西文生物医学期刊馆藏联合目录各家图书馆订阅的外文期刊纸质版复旦大学医科图书馆有电子检索,阅读的目的,了解临床证据-Cochrane Library，Clinical E
2、vidence，高IF SCI论文最新进展Pubmed-Abstract研究方法Methods讲演、兴趣-精读了解背景-Introduction相互比较-Discussion评价质量-Methods,文章的结构,Title and running titleAuthors and addressesAbstractKeywords and abbreviationsIntroductionMaterials and methodsResultsDiscussionAcknowledgmentsReferencesTables and figures,Title Abstract Figures
3、 Tables Results and discussion Rest of the paper,(J.K.Ladha),影响因子（Impact Factor）,发表文章篇数：2009=597，2010=577；合计=11742011年引用次数：2009=4341，2010=4122；合计=8463IF=8463/1174=7.2092012年6月中下旬公布,文章质量评价,Jadad评分Cochrane HandbookCochrane Back Review GroupCONSORT声明,Jadad 评分,随机分组序列的产生方法 2分：计算机或随机数字表1分：提到随机，但未详细说明0分：半随
4、机或未随机双盲2分：描述了实施双盲的具体方法并且被认为是恰当的，如采用完全一致的安慰剂等1分：试验仅提及采用双盲法0分：试验提及采用双盲，但方法不恰当，如比较片剂与注射剂而未提及使用双伪法退出与失访1分：详细说明了退出与失访的理由0分：没有提及,Cochrane Back Review Group,Furlan AD,Pennick V,Bombardier C,van Tulder M,the Editorial Board of the Cochrane Back Review Group.2009 Updated method guidelines for systematic revi
5、ews in the Cochrane Back Review Group.Spine 2009;34(18):192941.,CONSORT清单详细内容,引言,Broad information on topicPrevious researchNarrower background informationNeed for studyFocus of paperHypothesis and Purpose,Surgery is the treatment of choice for patients with disease stage I and II non-small cell lun
6、g cancer(NSCLC)An NSCLC meta-analysis combined the results from eight randomised trials of surgery versus surgery plus adjuvant cisplatin-based chemotherapy and showed a small,but not significant(p=0.08),absolute survival benefit of around 5%at 5 years(from 50%to 55%).At the time the current trial w
7、as designed(mid-1990s),adjuvant chemotherapy had not become standard clinical practice The clinical rationale for neo-adjuvant chemotherapy is three-fold:regression of the primary cancer could be achieved thereby facilitating and simplifying or reducing subsequent surgery;undetected micro-metastases
8、 could be dealt with at the start of treatment;and there might be inhibition of the putative stimulus to residual cancer by growth factors released by surgery and by subsequent wound healing The current trial was therefore set up to compare,in patients with resectable NSCLC,surgery alone versus thre
9、e cycles of platinum-based chemotherapy followed by surgery in terms of overall survival,quality of life,pathological staging,resectability rates,extent of surgery,and time to and site of relapse.,CONSORT清单详细内容,CONSORT清单详细内容（续一）,CONSORT清单详细内容（续二）,CONSORT清单详细内容（End）,CONSORT Group.CONSORT 2010 Stateme
10、nt:Updated Guidelines for Reporting Parallel Group Randomized Trials.Ann Intern Med.2010;152.David Moher,et al.CONSORT 2010 Explanation and Elaboration:updated guidelines for reporting parallel group randomised trials.BMJ 2010;340:c869,CONSORT流程图,好文章的要求（4C）,Clear：思路清晰、逻辑性强、概念清楚、层次 清楚、表达清楚、语句通顺Complete：内容完整、结构完整，忌虎头蛇尾Correct：内容正确，数据数据正确、可信，文法正确Concise：论述深刻、充分揭示其文章内涵,文章实例,Oseltamivir Compared With the Chinese Traditional Therapy Maxingshigan Yinqiaosan in the Treatment of H1N1 InfluenzaAnn Intern MedIF：16.729,
